Homeopathic medicine. Safe natural effective. Alcohol free. The letters HPUS indicate that the components in this product are officially monographed in the homoeopathic pharmacopoeia of the United States. integrativehealingsa.com. Questions? Call 1.888.841.4034. Made in USA. Other information: Do not use if tamper evident seal around neck is broken or missing. Store at room temperature.